InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ankfy1

Summary

InnateDB Protein

IDBP-532269.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ankfy1

Protein Name

ankyrin repeat and FYVE domain containing 1

Synonyms

Ankhzn; mKIAA1255; ZFYVE14;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118751

InnateDB Gene

IDBG-197054 (Ankfy1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:10092534}. Endosome membrane {ECO:0000269PubMed:10092534}; Peripheral membrane protein {ECO:0000269PubMed:10092534}. Note=Also associated with endosomal membranes.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006897

endocytosis

Cellular Component

GO:0005765	lysosomal membrane
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1337008

InterPro

IPR000210 BTB/POZ-like
IPR000306 FYVE zinc finger
IPR002110 Ankyrin repeat
IPR011011 Zinc finger, FYVE/PHD-type
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR017455 Zinc finger, FYVE-related
IPR020683 Ankyrin repeat-containing domain

PFAM

PF01363
PF00023
PF13606
PF00651
PF11929
PF12796

PRINTS

PR01415

PIRSF

SMART

SM00225
SM00064
SM00248

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt