InnateDB Protein
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IDBP-532873.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Nme5
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Protein Name
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non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
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Synonyms
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1700019D05Rik; Nm23-M5;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000117443
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InnateDB Gene
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IDBG-135118 (Nme5)
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Protein Structure
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Function |
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. {ECO:0000269PubMed:12788088}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Expressed predominantly in germ cells of the testis. Not expressed in testicular somatic cells. {ECO:0000269PubMed:12788088}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1922783
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InterPro |
IPR001564
Nucleoside diphosphate kinase
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PFAM |
PF00334
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PRINTS |
PR01243
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PIRSF |
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SMART |
SM00562
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TIGRFAMs |
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Modification |
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SwissProt |
Q99MH5
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PhosphoSite |
PhosphoSite-
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TrEMBL |
D6RHT7
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UniProt Splice Variant |
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Entrez Gene |
75533
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UniGene |
Mm.275430
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RefSeq |
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MGI ID |
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MGI Symbol |
Nme5
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC074335
AF343565
BC049625
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GenPept |
AAH49625
AAK20866
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