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InnateDB Protein
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IDBP-533151.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Spag9
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Protein Name
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sperm associated antigen 9
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Synonyms
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3110018C07Rik; 4733401I23Rik; 4831406C20Rik; AW552012; Jip4; JLP; JSAP2; JSAP2a; Mapk8ip4; syd1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000117502
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InnateDB Gene
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IDBG-208586 (Spag9)
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Protein Structure
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| Function |
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. {ECO:0000269PubMed:12391307, ECO:0000269PubMed:15767678}.
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| Subcellular Localization |
Cytoplasm. Cytoplasm, perinuclear region. Note=Perinuclear distribution in response to stress signals such as UV radiation.
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| Disease Associations |
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| Tissue Specificity |
Isoform 6 is highly expressed in brain, kidney, liver, heart. {ECO:0000269PubMed:15767678}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
13
[view]
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| Protein-Protein |
13
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
19 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1918084
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| InterPro |
IPR017986
WD40-repeat-containing domain
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q58A65
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| TrEMBL |
Z4YMB8
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| UniProt Splice Variant |
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| Entrez Gene |
70834
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| UniGene |
Mm.479010
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| RefSeq |
XP_006534273
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| MGI ID |
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| MGI Symbol |
Spag9
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL662838
BC060506
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| GenPept |
AAH60506
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Version 5.4