Version 5.4
| Mus musculus Protein: Dusp26 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-533291.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Dusp26 | ||||||||
| Protein Name | dual specificity phosphatase 26 (putative) | ||||||||
| Synonyms | 2310043K02Rik; Skrp3; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000124949 | ||||||||
| InnateDB Gene | IDBG-146465 (Dusp26) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Golgi apparatus {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Brain and skeletal muscle. In the brain it is expressed ubiquitously except in the hippocampus. {ECO:0000269PubMed:16581800, ECO:0000269PubMed:17001450}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1914209 | ||||||||
| InterPro |
IPR000340
Dual specificity phosphatase, catalytic domain IPR000387 Protein-tyrosine/Dual specificity phosphatase IPR020405 Atypical dual specificity phosphatase, subfamily A IPR020417 Atypical dual specificity phosphatase IPR020422 Dual specificity phosphatase, subgroup, catalytic domain IPR029021 Protein-tyrosine phosphatase-like |
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| PFAM |
PF00782
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| PRINTS |
PR01909
PR01908 |
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| PIRSF | |||||||||
| SMART |
SM00195
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9D700 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 66959 | ||||||||
| UniGene | Mm.23916 | ||||||||
| RefSeq | |||||||||
| MGI ID | |||||||||
| MGI Symbol | Dusp26 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22219 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB104416 AK009781 BC018204 | ||||||||
| GenPept | AAH18204 BAB26501 BAD91016 | ||||||||