Version 5.4
Mus musculus Protein: Pbk
Summary
InnateDB Protein IDBP-533715.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pbk
Protein Name PDZ binding kinase
Synonyms 2810434B10Rik; AW538537; D14Ertd732e; TOPK;
Species Mus musculus
Ensembl Protein ENSMUSP00000114484
InnateDB Gene IDBG-174520 (Pbk)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0001933 negative regulation of protein phosphorylation
GO:0006468 protein phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032873 negative regulation of stress-activated MAPK cascade
GO:0034644 cellular response to UV
GO:0050728 negative regulation of inflammatory response
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1289156
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR011009 Protein kinase-like domain
PFAM PF00069
PF07714
PRINTS PR00109
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YVF2
UniProt Splice Variant
Entrez Gene 52033
UniGene Mm.24337
RefSeq
MGI ID
MGI Symbol Pbk
OMIM
CCDS
HPRD
IMGT
EMBL AC125058
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca