Version 5.4
Mus musculus Protein: Vopp1
Summary
InnateDB Protein IDBP-533849.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vopp1
Protein Name vesicular, overexpressed in cancer, prosurvival protein 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000115377
InnateDB Gene IDBG-151473 (Vopp1)
Protein Structure
UniProt Annotation
Function Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=When overexpressed, localizes in the nucleus and perinuclear regions. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
Cellular Component
GO:0005768 endosome
GO:0030659 cytoplasmic vesicle membrane
GO:0031301 integral component of organelle membrane
Protein Structure and Domains
PDB ID MGI:2141658
InterPro IPR021684 Uncharacterised protein family WW domain-binding protein 1
PFAM PF11669
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R1C3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 232023
UniGene Mm.470655
RefSeq XP_006506016
MGI ID
MGI Symbol Vopp1
OMIM
CCDS
HPRD
IMGT
EMBL AK030975 AK031812 AK158041 AK170152 AK170832 BC024822
GenPept AAH24822 BAC27198 BAC27562 BAE34331 BAE41599 BAE42060

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca