InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Grhpr

Summary

InnateDB Protein

IDBP-534093.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Grhpr

Protein Name

glyoxylate reductase/hydroxypyruvate reductase

Synonyms

1110059D05Rik; 6430629L09Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120254

InnateDB Gene

IDBG-143633 (Grhpr)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287	NAD binding

Biological Process

GO:0006098	pentose-phosphate shunt
GO:0008152	metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1923488

InterPro

IPR006115 6-phosphogluconate dehydrogenase, NADP-binding
IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal

PFAM

PF03446
PF00389
PF02826
PF03807

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-