InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myh9

Summary

InnateDB Protein

IDBP-534111.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myh9

Protein Name

myosin, heavy polypeptide 9, non-muscle

Synonyms

Fltn; Myhn-1; Myhn1; NMHCIIA; NMMHC-A; NMMHC-IIA; TU72.6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116198

InnateDB Gene

IDBG-158163 (Myh9)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 92 interaction(s) predicted by orthology.

Experimentally validated
Total	35 [view]
Protein-Protein	35 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	92 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0000212	meiotic spindle organization
GO:0000904	cell morphogenesis involved in differentiation
GO:0001701	in utero embryonic development
GO:0001768	establishment of T cell polarity
GO:0006928	cellular component movement
GO:0007155	cell adhesion
GO:0007520	myoblast fusion
GO:0008152	metabolic process
GO:0008360	regulation of cell shape
GO:0016337	single organismal cell-cell adhesion
GO:0032796	uropod organization
GO:0051295	establishment of meiotic spindle localization

Cellular Component

GO:0001725	stress fiber
GO:0001772	immunological synapse
GO:0001931	uropod
GO:0005737	cytoplasm
GO:0005819	spindle
GO:0005886	plasma membrane
GO:0005913	cell-cell adherens junction
GO:0005938	cell cortex
GO:0016459	myosin complex
GO:0016460	myosin II complex
GO:0030863	cortical cytoskeleton
GO:0031594	neuromuscular junction

Protein Structure and Domains

PDB ID

MGI:107717

InterPro

IPR001609 Myosin head, motor domain
IPR004009 Myosin, N-terminal, SH3-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00063
PF02736

PRINTS

PR00193

PIRSF

SMART

SM00242

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F2Z494

UniProt Splice Variant

Entrez Gene

17886

UniGene

Mm.392841

RefSeq

MGI ID

MGI Symbol

Myh9

OMIM

CCDS

HPRD

IMGT

EMBL

AL583886

GenPept