Version 5.4
Mus musculus Protein: Pycr1
Summary
InnateDB Protein IDBP-534688.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pycr1
Protein Name pyrroline-5-carboxylate reductase 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000117737
InnateDB Gene IDBG-214865 (Pycr1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004735 pyrroline-5-carboxylate reductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042802 identical protein binding
GO:0051287 NAD binding
Biological Process
GO:0006561 proline biosynthetic process
GO:0034599 cellular response to oxidative stress
GO:0046168 glycerol-3-phosphate catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:2384795
InterPro IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal
PFAM PF01210
PF03807
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2ABZ3
UniProt Splice Variant
Entrez Gene 209027
UniGene Mm.127731
RefSeq
MGI ID
MGI Symbol Pycr1
OMIM
CCDS
HPRD
IMGT
EMBL AL663030
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca