InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccm2

Summary

InnateDB Protein

IDBP-534792.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccm2

Protein Name

cerebral cavernous malformation 2 homolog (human)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125072

InnateDB Gene

IDBG-148293 (Ccm2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001568	blood vessel development
GO:0001570	vasculogenesis
GO:0001701	in utero embryonic development
GO:0001885	endothelial cell development
GO:0001944	vasculature development
GO:0007507	heart development
GO:0035264	multicellular organism growth
GO:0045216	cell-cell junction organization
GO:0048839	inner ear development
GO:0048845	venous blood vessel morphogenesis
GO:0060039	pericardium development
GO:0060837	blood vessel endothelial cell differentiation
GO:0061154	endothelial tube morphogenesis

Cellular Component

GO:0043234

protein complex

Protein Structure and Domains

PDB ID

MGI:2384924

InterPro

IPR006020 PTB/PI domain

PFAM

PF00640
PF14719

PRINTS

PIRSF

SMART

SM00462

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CXR5

UniProt Splice Variant

Entrez Gene

216527

UniGene

Mm.221271

RefSeq

MGI ID

MGI Symbol

Ccm2

OMIM

CCDS

HPRD

IMGT

EMBL

AL603787 AL646047

GenPept