InnateDB Protein
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IDBP-534893.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Fbf1
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Protein Name
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Fas (TNFRSF6) binding factor 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000114558
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InnateDB Gene
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IDBG-214414 (Fbf1)
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Protein Structure
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Function |
Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269PubMed:10978533}. Cell junction {ECO:0000250}. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to the apical junction complex (AJC) in epithelial cells (By similarity). {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Broadly expressed. {ECO:0000269PubMed:10978533}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
20 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1922033
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-A2A870
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TrEMBL |
Z4YLK3
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UniProt Splice Variant |
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Entrez Gene |
217335
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UniGene |
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RefSeq |
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MGI ID |
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MGI Symbol |
Fbf1
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL607108
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GenPept |
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