InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Med6

Summary

InnateDB Protein

IDBP-535227.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Med6

Protein Name

mediator of RNA polymerase II transcription, subunit 6 homolog (yeast)

Synonyms

1500012F11Rik; AU019660; AV213303;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125103

InnateDB Gene

IDBG-154516 (Med6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	48 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001104	RNA polymerase II transcription cofactor activity
GO:0003677	DNA binding
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008134	transcription factor binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0019827	stem cell maintenance
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0016592	mediator complex

Protein Structure and Domains

PDB ID

MGI:1917042

InterPro

IPR007018 Mediator complex, subunit Med6

PFAM

PF04934

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CXQ3

UniProt Splice Variant

Entrez Gene

69792

UniGene

RefSeq

MGI ID

MGI Symbol

Med6

OMIM

CCDS

HPRD

IMGT

EMBL

AC154908

GenPept