InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Apbb2

Summary

InnateDB Protein

IDBP-535905.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Apbb2

Protein Name

amyloid beta (A4) precursor protein-binding, family B, member 2

Synonyms

2310007D03Rik; FE65L1; Rirl1; TR2L; Zfra;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123978

InnateDB Gene

IDBG-167349 (Apbb2)

Protein Structure

UniProt Annotation

Function

May modulate the internalization of beta-amyloid precursor protein. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0035035	histone acetyltransferase binding

Biological Process

GO:0001764	neuron migration
GO:0006355	regulation of transcription, DNA-templated
GO:0007050	cell cycle arrest
GO:0007411	axon guidance
GO:0030048	actin filament-based movement
GO:0030198	extracellular matrix organization
GO:0030308	negative regulation of cell growth
GO:0043065	positive regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0050821	protein stabilization