InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fam111a

Summary

InnateDB Protein

IDBP-536031.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fam111a

Protein Name

family with sequence similarity 111, member A

Synonyms

4632417K18Rik; AW413625;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119518

InnateDB Gene

IDBG-147967 (Fam111a)

Protein Structure

UniProt Annotation

Function

Chromatin-associated protein required for PCNA loading on replication sites. Promotes S-phase entry and DNA synthesis (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly localizes to nucleus: colocalizes with PCNA on replication sites. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003723	RNA binding
GO:0003724	RNA helicase activity
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0000087	mitotic M phase
GO:0006260	DNA replication
GO:0006508	proteolysis
GO:0008152	metabolic process
GO:0045071	negative regulation of viral genome replication