InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hars2

Summary

InnateDB Protein

IDBP-536114.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hars2

Protein Name

histidyl-tRNA synthetase 2, mitochondrial (putative)

Synonyms

4631412B19Rik; AI593507; Harsl; HARSR; HO3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117231

InnateDB Gene

IDBG-139068 (Hars2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004821	histidine-tRNA ligase activity
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006427	histidyl-tRNA aminoacylation

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

MGI:1918041

InterPro

IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR004154 Anticodon-binding
IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit
IPR006195 Aminoacyl-tRNA synthetase, class II
IPR015807 Histidine-tRNA ligase

PFAM

PF00587
PF03129

PRINTS

PIRSF

PIRSF001549

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99KK9