Version 5.4
Mus musculus Protein: Asb18
Summary
InnateDB Protein IDBP-536467.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Asb18
Protein Name ankyrin repeat and SOCS box-containing 18
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000117767
InnateDB Gene IDBG-179835 (Asb18)
Protein Structure
UniProt Annotation
Function May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2655109
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VHA6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 208372
UniGene
RefSeq
MGI ID
MGI Symbol Asb18
OMIM
CCDS
HPRD
IMGT
EMBL AY057054 BC107370 BC107371 BC127152
GenPept AAI07371 AAI07372 AAI27153 AAL18249

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca