InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cmklr1

Summary

InnateDB Protein

IDBP-536843.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cmklr1

Protein Name

chemokine-like receptor 1

Synonyms

ChemR23; DEZ; Gpcr27; mcmklr1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121765

InnateDB Gene

IDBG-191760 (Cmklr1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004950	chemokine receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0007186	G-protein coupled receptor signaling pathway
GO:0010759	positive regulation of macrophage chemotaxis
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0050848	regulation of calcium-mediated signaling
GO:0070098	chemokine-mediated signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:109603

InterPro

IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001274 C5a1/C5a2 anaphylatoxin chemotactic receptor
IPR002234 Anaphylatoxin chemotactic receptor family
IPR002258 DEZ orphan receptor
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00241
PR00237
PR00426
PR01104
PR01126

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite