InnateDB Protein
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IDBP-536901.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pgap2
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Protein Name
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post-GPI attachment to proteins 2
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000121521
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InnateDB Gene
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IDBG-202705 (Pgap2)
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Protein Structure
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Function |
Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity). {ECO:0000250}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
GO:0006506
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GPI anchor biosynthetic process
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GO:0006974
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cellular response to DNA damage stimulus
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GO:0008630
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intrinsic apoptotic signaling pathway in response to DNA damage
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GO:0015031
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protein transport
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GO:0042770
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signal transduction in response to DNA damage
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GO:0042771
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intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
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GO:1902230
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negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
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Cellular Component |
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PDB ID |
MGI:2385286
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InterPro |
IPR019402
Frag1/DRAM/Sfk1
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PFAM |
PF10277
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3TQR0
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PhosphoSite |
PhosphoSite-
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TrEMBL |
D3Z4K4
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UniProt Splice Variant |
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Entrez Gene |
233575
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UniGene |
Mm.487964
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RefSeq |
NP_663558
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MGI ID |
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MGI Symbol |
Pgap2
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OMIM |
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CCDS |
CCDS40048
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HPRD |
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IMGT |
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EMBL |
AC118592
AC139579
AK134287
AK146442
AK152420
AK159933
AK159950
AK163373
BC004794
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GenPept |
AAH04794
BAE22083
BAE27175
BAE31205
BAE35494
BAE35506
BAE37322
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