InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Igf2r

Summary

InnateDB Protein

IDBP-537439.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Igf2r

Protein Name

insulin-like growth factor 2 receptor

Synonyms

AI661837; CD222; CI-MPR; M6P/IGF2R; Mpr300;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124679

InnateDB Gene

IDBG-136984 (Igf2r)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005215	transporter activity
GO:0005520	insulin-like growth factor binding
GO:0005537	mannose binding

Biological Process

GO:0006810

transport

Cellular Component

GO:0005634	nucleus
GO:0005641	nuclear envelope lumen
GO:0005737	cytoplasm
GO:0005768	endosome
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030140	trans-Golgi network transport vesicle

Protein Structure and Domains

PDB ID

MGI:96435

InterPro

IPR000479 Cation-independent mannose-6-phosphate receptor
IPR009011 Mannose-6-phosphate receptor binding domain

PFAM

PF00878

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CXV7

UniProt Splice Variant

Entrez Gene

16004

UniGene

Mm.473474

RefSeq

MGI ID

MGI Symbol

Igf2r

OMIM

CCDS

HPRD

IMGT

EMBL

AC116804 AC167817

GenPept