Version 5.4
Mus musculus Protein: Hrasls
Summary
InnateDB Protein IDBP-538157.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hrasls
Protein Name HRAS-like suppressor
Synonyms 2810012B06Rik; A-C1; Hrasrs; HRSL1;
Species Mus musculus
Ensembl Protein ENSMUSP00000123809
InnateDB Gene IDBG-150901 (Hrasls)
Protein Structure
UniProt Annotation
Function Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs. {ECO:0000269PubMed:21880860}.
Subcellular Localization Cytoplasm. Membrane {ECO:0000250}; Single- pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in skeletal muscle, heart, brain and bone marrow.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004620 phospholipase activity
GO:0016740 transferase activity
Biological Process
GO:0001558 regulation of cell growth
GO:0007031 peroxisome organization
GO:0007265 Ras protein signal transduction
GO:0016042 lipid catabolic process
GO:0046485 ether lipid metabolic process
Cellular Component
GO:0005641 nuclear envelope lumen
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1351473
InterPro IPR007053 LRAT-like domain
PFAM PF04970
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZU4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 27281
UniGene Mm.416642
RefSeq
MGI ID
MGI Symbol Hrasls
OMIM
CCDS CCDS28094
HPRD
IMGT
EMBL AB510982 AC154448 AF163095 AK004528 AK039471 BC048482 CH466521
GenPept AAF13304 AAH48482 BAB23348 BAC30361 BAI63211 EDK97707 EDK97708

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca