Version 5.4
Mus musculus Protein: Drosha
Summary
InnateDB Protein IDBP-539979.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Drosha
Protein Name drosha, ribonuclease type III
Synonyms 1110013A17Rik; AI874853; Etohi2; Rn3; Rnasen;
Species Mus musculus
Ensembl Protein ENSMUSP00000121499
InnateDB Gene IDBG-130254 (Drosha)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004525 ribonuclease III activity
Biological Process
GO:0006396 RNA processing
Cellular Component
Protein Structure and Domains
PDB ID MGI:1261425
InterPro IPR000999 Ribonuclease III domain
IPR014720 Double-stranded RNA-binding domain
PFAM PF00636
PF14622
PF00035
PRINTS
PIRSF
SMART SM00535
SM00358
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9CTG2
UniProt Splice Variant
Entrez Gene 14000
UniGene Mm.293142
RefSeq
MGI ID
MGI Symbol Drosha
OMIM
CCDS
HPRD
IMGT
EMBL AK003651 BC055696 BC057687
GenPept AAH55696 AAH57687 BAB22917

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca