Version 5.4
Homo sapiens Protein: CIC
Summary
InnateDB Protein IDBP-54032.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CIC
Protein Name capicua homolog (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000160740
InnateDB Gene IDBG-54030 (CIC)
Protein Structure
UniProt Annotation
Function Transcriptional repressor which may play a role in development of the central nervous system (CNS).
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00267}.
Disease Associations
Tissue Specificity Expressed in fetal brain. {ECO:0000269PubMed:15981098}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q96RK0
TrEMBL
UniProt Splice Variant
Entrez Gene 23152
UniGene Hs.388236
RefSeq XP_005258730
HUGO HGNC:14214
OMIM 612082
CCDS
HPRD 10831
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca