Version 5.4
Mus musculus Protein: Ept1
Summary
InnateDB Protein IDBP-540621.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ept1
Protein Name ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
Synonyms 4933402G07Rik; AI448296; AI452230; C79563; D5Wsu178e; mKIAA1724; SELI;
Species Mus musculus
Ensembl Protein ENSMUSP00000118368
InnateDB Gene IDBG-145503 (Ept1)
Protein Structure
UniProt Annotation
Function Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via 'Kennedy' pathway (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004307 ethanolaminephosphotransferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
GO:0046872 metal ion binding
Biological Process
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0008150 biological_process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:107898
InterPro IPR000462 CDP-alcohol phosphatidyltransferase
IPR014472 Choline/ethanolamine phosphotransferase
PFAM PF01066
PRINTS
PIRSF PIRSF015665
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80TA1
PhosphoSite PhosphoSite-Q80TA1
TrEMBL Q9D4D0
UniProt Splice Variant
Entrez Gene 28042
UniGene Mm.472151
RefSeq NP_081928
MGI ID
MGI Symbol Ept1
OMIM
CCDS CCDS51451
HPRD
IMGT
EMBL AK016617 AK048011 AK079325 AK122544 BC106097 BC115783 BC117551
GenPept AAI06098 AAI15784 AAI17552 BAB30340 BAC33214 BAC37608 BAC65826

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca