InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd86

Summary

InnateDB Protein

IDBP-540651.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd86

Protein Name

CD86 antigen

Synonyms

B7; B7-2; B7.2; B70; Cd28l2; CLS1; ETC-1; Ly-58; Ly58; MB7; MB7-2; TS/A-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117756

InnateDB Gene

IDBG-158071 (Cd86)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	1 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0002224	toll-like receptor signaling pathway
GO:0042102	positive regulation of T cell proliferation
GO:0042113	B cell activation
GO:0051607	defense response to virus

Cellular Component

GO:0009897	external side of plasma membrane
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:101773

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain

PFAM

PF07686

PRINTS

PIRSF

SMART

SM00406

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z363

UniProt Splice Variant

Entrez Gene

12524

UniGene

RefSeq

MGI ID

MGI Symbol

Cd86

OMIM

CCDS

HPRD

IMGT

EMBL

AC117662

GenPept