InnateDB Protein
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IDBP-540688.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Syce2
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Protein Name
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synaptonemal complex central element protein 2
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Synonyms
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1700013H19Rik; AA407907; Cesc1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000122159
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InnateDB Gene
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IDBG-175109 (Syce2)
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Protein Structure
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Function |
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination. {ECO:0000269PubMed:15944401}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:15944401}. Chromosome {ECO:0000269PubMed:15944401}. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE1 in the central elements.
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Disease Associations |
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Tissue Specificity |
Meiotic cells (at protein level). Expressed in the ovary and testis. {ECO:0000269PubMed:15944401}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1919096
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q505B8
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PhosphoSite |
PhosphoSite-Q505B8
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
71846
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UniGene |
Mm.451910
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RefSeq |
NP_082230
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MGI ID |
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MGI Symbol |
Syce2
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OMIM |
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CCDS |
CCDS22481
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HPRD |
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IMGT |
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EMBL |
AK005954
AK167332
BC094628
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GenPept |
AAH94628
BAB24337
BAE39434
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