InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pycr1

Summary

InnateDB Protein

IDBP-540979.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pycr1

Protein Name

pyrroline-5-carboxylate reductase 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120558

InnateDB Gene

IDBG-214865 (Pycr1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004735	pyrroline-5-carboxylate reductase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042802	identical protein binding
GO:0051287	NAD binding

Biological Process

GO:0006561	proline biosynthetic process
GO:0034599	cellular response to oxidative stress
GO:0046168	glycerol-3-phosphate catabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:2384795

InterPro

IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal

PFAM

PF01210
PF03807

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-