Mus musculus Protein: Slc25a25
Summary
InnateDB Protein IDBP-541578.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc25a25
Protein Name solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000115617
InnateDB Gene IDBG-160162 (Slc25a25)
Protein Structure
UniProt Annotation
Function Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0055085 transmembrane transport
Cellular Component
Protein Structure and Domains
PDB ID MGI:1915913
InterPro IPR002048 EF-hand domain
IPR002067 Mitochondrial carrier protein
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00036
PF13202
PF13405
PF00153
PRINTS PR00926
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-A2ASZ8
TrEMBL Z4YLR9
UniProt Splice Variant
Entrez Gene 227731
UniGene
RefSeq
MGI ID
MGI Symbol Slc25a25
OMIM
CCDS
HPRD
IMGT
EMBL AL928710
GenPept