InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adcy3

Summary

InnateDB Protein

IDBP-541671.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adcy3

Protein Name

adenylate cyclase 3

Synonyms

AC3; mKIAA0511;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115644

InnateDB Gene

IDBG-127880 (Adcy3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004016	adenylate cyclase activity
GO:0005515	protein binding
GO:0016849	phosphorus-oxygen lyase activity

Biological Process

GO:0006171	cAMP biosynthetic process
GO:0007190	activation of adenylate cyclase activity
GO:0007608	sensory perception of smell
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005886	plasma membrane
GO:0005929	cilium
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:99675

InterPro

IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase

PFAM

PF00211

PRINTS

PIRSF

SMART

SM00044

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

MGI ID

MGI Symbol

OMIM

CCDS

HPRD

IMGT

EMBL

AF253540 AK122298 CH466623 CT572999

GenPept

AAF65474 BAC65580 EDL01375 EDL01376

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca