Version 5.4
Mus musculus Protein: Ankfy1
Summary
InnateDB Protein IDBP-542135.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ankfy1
Protein Name ankyrin repeat and FYVE domain containing 1
Synonyms Ankhzn; mKIAA1255; ZFYVE14;
Species Mus musculus
Ensembl Protein ENSMUSP00000118252
InnateDB Gene IDBG-197054 (Ankfy1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:10092534}. Endosome membrane {ECO:0000269PubMed:10092534}; Peripheral membrane protein {ECO:0000269PubMed:10092534}. Note=Also associated with endosomal membranes.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006897 endocytosis
Cellular Component
GO:0005765 lysosomal membrane
GO:0010008 endosome membrane
Protein Structure and Domains
PDB ID MGI:1337008
InterPro IPR000210 BTB/POZ-like
IPR002110 Ankyrin repeat
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF00651
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00225
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q810B6
PhosphoSite PhosphoSite-Q810B6
TrEMBL
UniProt Splice Variant
Entrez Gene 11736
UniGene Mm.414874
RefSeq
MGI ID
MGI Symbol Ankfy1
OMIM
CCDS
HPRD
IMGT
EMBL AB011370 AB098157 AB098329 AK122479 AL663082 AL808023 BC139231
GenPept AAI39232 BAA24980 BAC65761 BAC67211 BAC67388 BAC67389 CAI25188 CAI25205

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca