InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fam129a

Summary

InnateDB Protein

IDBP-542232.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fam129a

Protein Name

family with sequence similarity 129, member A

Synonyms

AI256368; AU019833; Niban;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115822

InnateDB Gene

IDBG-198150 (Fam129a)

Protein Structure

UniProt Annotation

Function

Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response. {ECO:0000269PubMed:17588536}.

Subcellular Localization

Cytoplasm {ECO:0000250UniProtKB:Q9ESN0}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0001933	negative regulation of protein phosphorylation
GO:0001934	positive regulation of protein phosphorylation
GO:0034976	response to endoplasmic reticulum stress
GO:0045727	positive regulation of translation