InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pgs1

Summary

InnateDB Protein

IDBP-542251.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pgs1

Protein Name

phosphatidylglycerophosphate synthase 1

Synonyms

2610019F11Rik; 4933424M23Rik; SAF;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121973

InnateDB Gene

IDBG-214607 (Pgs1)

Protein Structure

UniProt Annotation

Function

Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed with higher expression in testis, liver and brain. {ECO:0000269PubMed:9880566}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003824	catalytic activity
GO:0005524	ATP binding
GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
GO:0016780	phosphotransferase activity, for other substituted phosphate groups

Biological Process

GO:0006655	phosphatidylglycerol biosynthetic process
GO:0008150	biological_process
GO:0008152	metabolic process
GO:0008654	phospholipid biosynthetic process
GO:0032049	cardiolipin biosynthetic process
GO:0046339	diacylglycerol metabolic process