InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndufb5

Summary

InnateDB Protein

IDBP-542622.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufb5

Protein Name

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5

Synonyms

0610007D05Rik; AU015782; SGDH;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114963

InnateDB Gene

IDBG-137131 (Ndufb5)

Protein Structure

UniProt Annotation

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0008150	biological_process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0016021	integral component of membrane