InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Eri3

Summary

InnateDB Protein

IDBP-543007.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Eri3

Protein Name

exoribonuclease 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115520

InnateDB Gene

IDBG-179820 (Eri3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Highly expressed in the brain, heart, thyroid and testis. Expressed at low levels in the muscle cells, liver, pancreas and kidney. {ECO:0000269PubMed:11571277}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0008150	biological_process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0005886

plasma membrane

Protein Structure and Domains

PDB ID

MGI:2153887

InterPro

IPR012337 Ribonuclease H-like domain
IPR013520 Exonuclease, RNase T/DNA polymerase III

PFAM

PF00929

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8C460

PhosphoSite

PhosphoSite-Q8C460

TrEMBL

UniProt Splice Variant

Entrez Gene

140546

UniGene

RefSeq

MGI ID

MGI Symbol

Eri3

OMIM

CCDS

HPRD

IMGT

EMBL

AK083017 AK144107 AL645740 AL671520 AY029599 BC079640 BC116685 BC117540

GenPept

AAH79640 AAI16686 AAI17541 AAK38347 BAC38733 BAE25703 CAM23618 CAM27524 CAM27526 CAM27529