Version 5.4
Mus musculus Protein: Acvr1c
Summary
InnateDB Protein IDBP-543020.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acvr1c
Protein Name activin A receptor, type IC
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000119776
InnateDB Gene IDBG-172013 (Acvr1c)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004675 transmembrane receptor protein serine/threonine kinase activity
GO:0004702 receptor signaling protein serine/threonine kinase activity
GO:0005024 transforming growth factor beta-activated receptor activity
GO:0005524 ATP binding
GO:0016361 activin receptor activity, type I
GO:0038100 nodal binding
Biological Process
GO:0002021 response to dietary excess
GO:0009749 response to glucose
GO:0019915 lipid storage
GO:0023014 signal transduction by phosphorylation
GO:0030154 cell differentiation
GO:0030262 apoptotic nuclear changes
GO:0032868 response to insulin
GO:0038092 nodal signaling pathway
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046676 negative regulation of insulin secretion
GO:1901164 negative regulation of trophoblast cell migration
GO:1901383 negative regulation of chorionic trophoblast cell proliferation
Cellular Component
GO:0016020 membrane
GO:0048179 activin receptor complex
Protein Structure and Domains
PDB ID MGI:2661081
InterPro IPR000472 TGF-beta receptor/activin receptor, type I/II
PFAM PF01064
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z1K2
UniProt Splice Variant
Entrez Gene 269275
UniGene Mm.77751
RefSeq
MGI ID
MGI Symbol Acvr1c
OMIM
CCDS
HPRD
IMGT
EMBL AL772179
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca