InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GJC1

Summary

InnateDB Protein

IDBP-54325.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GJC1

Protein Name

gap junction protein, gamma 1, 45kDa

Synonyms

CX45; GJA7;

Species

Homo sapiens

Ensembl Protein

ENSP00000333193

InnateDB Gene

IDBG-54323 (GJC1)

Protein Structure

UniProt Annotation

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Subcellular Localization

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006810	transport
GO:0006936	muscle contraction
GO:0007043	cell-cell junction assembly
GO:0007268	synaptic transmission
GO:0016264	gap junction assembly
GO:0061024	membrane organization
GO:0086014	atrial cardiac muscle cell action potential

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0005886	plasma membrane
GO:0005921	gap junction
GO:0014704	intercalated disc
GO:0016021	integral component of membrane