Version 5.4
Homo sapiens Protein: LRFN5
Summary
InnateDB Protein IDBP-5433.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRFN5
Protein Name leucine rich repeat and fibronectin type III domain containing 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000298119
InnateDB Gene IDBG-5431 (LRFN5)
Protein Structure
UniProt Annotation
Function Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons. {ECO:0000269PubMed:18227064, ECO:0000269PubMed:18585462}.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin
PFAM PF00560
PF13504
PF13855
PF00041
PF01108
PF07679
PF00047
PRINTS
PIRSF
SMART SM00369
SM00408
SM00409
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96NI6
PhosphoSite PhosphoSite-Q96NI6
TrEMBL
UniProt Splice Variant
Entrez Gene 145581
UniGene Hs.136893
RefSeq NP_689660
HUGO HGNC:20360
OMIM 612811
CCDS CCDS9678
HPRD 17445
IMGT
EMBL AK055365 AK096627 AL138498 BC043165
GenPept AAH43165 BAB70910 BAG53340

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca