Version 5.4
Homo sapiens Protein: CXCL17
Summary
InnateDB Protein IDBP-54353.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CXCL17
Protein Name chemokine (C-X-C motif) ligand 17
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000345317
InnateDB Gene IDBG-54351 (CXCL17)
Protein Structure
UniProt Annotation
Function Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. {ECO:0000269PubMed:16455961, ECO:0000269PubMed:16989774, ECO:0000269PubMed:17307946}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up- regulation. {ECO:0000269PubMed:16455961, ECO:0000269PubMed:16989774}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL X6R584
UniProt Splice Variant
Entrez Gene 284340
UniGene
RefSeq
HUGO HGNC:19232
OMIM 611387
CCDS
HPRD 18264
IMGT
EMBL AC011497
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca