Version 5.4
Homo sapiens Protein: KIAA1033
Summary
InnateDB Protein IDBP-54581.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIAA1033
Protein Name KIAA1033
Synonyms MRT43; SWIP;
Species Homo sapiens
Ensembl Protein ENSP00000328062
InnateDB Gene IDBG-54579 (KIAA1033)
Protein Structure
UniProt Annotation
Function Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016197 endosomal transport
Cellular Component
GO:0005768 endosome
GO:0071203 WASH complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2M389
PhosphoSite PhosphoSite-Q2M389
TrEMBL F8W1W1
UniProt Splice Variant
Entrez Gene 23325
UniGene Hs.614405
RefSeq NP_056090
HUGO HGNC:29174
OMIM 615748
CCDS CCDS41826
HPRD 13829
IMGT
EMBL AB028956 AC016257 AK001657 BC031358 BC040936 BC104992 BC104994 BC110850
GenPept AAH31358 AAH40936 AAI04993 AAI04995 AAI10851 BAA82985 BAA91816

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca