Version 5.4
Homo sapiens Protein: ESF1
Summary
InnateDB Protein IDBP-54781.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ESF1
Protein Name ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000202816
InnateDB Gene IDBG-54779 (ESF1)
Protein Structure
UniProt Annotation
Function May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR012580 NUC153
PFAM PF08159
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H501
PhosphoSite PhosphoSite-Q9H501
TrEMBL
UniProt Splice Variant
Entrez Gene 51575
UniGene Hs.606424
RefSeq NP_057733
HUGO HGNC:15898
OMIM
CCDS CCDS13117
HPRD 10732
IMGT
EMBL AF068285 AK000375 AK022369 AK022670 AL161659 BC046107
GenPept AAF65504 AAH46107 BAA91123 BAB14023 BAB14167 CAC07199

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca