Version 5.4
Homo sapiens Protein: TUSC1
Summary
InnateDB Protein IDBP-54884.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUSC1
Protein Name tumor suppressor candidate 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000350716
InnateDB Gene IDBG-54882 (TUSC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Widely expressed at low level. Expressed at higher level in testis, weakly expressed in muscle, colon, lung and spleen. Not detected in 3 non small cell lung carcinoma (NSCLC) cell lines with homozygous deletion of the 9p region, while it is down-regulated in 3 other tumor cell lines. {ECO:0000269PubMed:15208665}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2TAM9
PhosphoSite PhosphoSite-Q2TAM9
TrEMBL
UniProt Splice Variant
Entrez Gene 286319
UniGene Hs.606014
RefSeq NP_001004125
HUGO HGNC:31010
OMIM 610529
CCDS CCDS34999
HPRD 18247
IMGT
EMBL AL590322 AY168647 BC017510 BC028316 BC046919 BC110824
GenPept AAH17510 AAH28316 AAH46919 AAI10825 AAO38227

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca