InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SP2

Summary

InnateDB Protein

IDBP-56382.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SP2

Protein Name

Sp2 transcription factor

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000365931

InnateDB Gene

IDBG-56378 (SP2)

Protein Structure

UniProt Annotation

Function

Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	12 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0042826	histone deacetylase binding
GO:0046872	metal ion binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006955	immune response
GO:0035264	multicellular organism growth
GO:0048144	fibroblast proliferation
GO:0048568	embryonic organ development
GO:0072358	cardiovascular system development