Homo sapiens Protein: ALDH2
Summary
InnateDB Protein IDBP-57712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH2
Protein Name aldehyde dehydrogenase 2 family (mitochondrial)
Synonyms ALDH-E2; ALDHI; ALDM;
Species Homo sapiens
Ensembl Protein ENSP00000261733
InnateDB Gene IDBG-57710 (ALDH2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity
GO:0009055 electron carrier activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006066 alcohol metabolic process
GO:0006068 ethanol catabolic process
GO:0006069 ethanol oxidation
GO:0006805 xenobiotic metabolic process
GO:0007268 synaptic transmission
GO:0008152 metabolic process
GO:0042136 neurotransmitter biosynthetic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF00171
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P05091
PhosphoSite PhosphoSite-P05091
TrEMBL Q9UN17
UniProt Splice Variant
Entrez Gene 217
UniGene Hs.604551
RefSeq NP_000681
HUGO HGNC:404
OMIM 100650
CCDS CCDS9155
HPRD 00003
IMGT
EMBL AC002996 AC003029 AF164120 AK301375 AY621070 BC002967 BC071839 CR456991 EU373804 EU373808 EU373810 EU373812 EU414249 EU414250 EU414251 EU414252 EU414253 EU414254 EU414255 EU414256 EU414257 EU414258 K03001 M20444 M20445 M20446 M20447 M20448 M20449 M20450 M20451 M20452 M20453 M20454 M20456 M26760 M54931 X05409 Y00109
GenPept AAA51693 AAA51694 AAA62825 AAB59500 AAD48447 AAH02967 AAH71839 AAT41621 ABY79820 ABY79824 ABY79826 ABY79828 ACF25889 ACF25890 ACF25891 ACF25892 ACF25893 ACF25894 ACF25895 ACF25896 ACF25897 ACF25898 BAG62916 CAA28990 CAA68290 CAG33272