Version 5.4
Homo sapiens Protein: RNFT1
Summary
InnateDB Protein IDBP-583218.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNFT1
Protein Name ring finger protein, transmembrane 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000436144
InnateDB Gene IDBG-62022 (RNFT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed at highest levels in testis, lower levels in heart, liver, lung, and kidney. Not detected in brain, ovary, and uterus. Down-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS). {ECO:0000269PubMed:17074343}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5M7Z0
PhosphoSite PhosphoSite-Q5M7Z0
TrEMBL
UniProt Splice Variant
Entrez Gene 51136
UniGene Hs.657803
RefSeq
HUGO HGNC:30206
OMIM 615172
CCDS
HPRD 17925
IMGT
EMBL AC004686 AC005702 AF100745 AK098649 BC006971 BC088365 CH471109
GenPept AAD43009 AAH88365 BAC05364 EAW94381

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca