InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RELA

Summary

InnateDB Protein

IDBP-584460.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RELA

Protein Name

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Synonyms

NFKB3; p65;

Species

Homo sapiens

Ensembl Protein

ENSP00000432537

InnateDB Gene

IDBG-57543 (RELA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 570 experimentally validated interaction(s) in this database.
They are also associated with 108 interaction(s) predicted by orthology.

Experimentally validated
Total	570 [view]
Protein-Protein	407 [view]
Protein-DNA	157 [view]
Protein-RNA	0
DNA-DNA	6 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	108 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000451 NF-kappa-B/Rel/Dorsal
IPR002909 IPT domain
IPR008967 p53-like transcription factor, DNA-binding
IPR011539 Rel homology domain
IPR014756 Immunoglobulin E-set

PFAM

PF01833
PF00554

PRINTS

PR00057

PIRSF

SMART

SM00429

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt