InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HMGA2

Summary

InnateDB Protein

IDBP-585745.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HMGA2

Protein Name

high mobility group AT-hook 2

Synonyms

BABL; HMGI-C; HMGIC; LIPO; STQTL9;

Species

Homo sapiens

Ensembl Protein

ENSP00000437621

InnateDB Gene

IDBG-45426 (HMGA2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	23 [view]
Protein-Protein	22 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0019899	enzyme binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007165	signal transduction
GO:0007283	spermatogenesis
GO:0008283	cell proliferation
GO:0008284	positive regulation of cell proliferation
GO:0008584	male gonad development
GO:0010564	regulation of cell cycle process
GO:0010628	positive regulation of gene expression
GO:0021846	cell proliferation in forebrain
GO:0021983	pituitary gland development
GO:0030325	adrenal gland development
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway
GO:0035019	somatic stem cell maintenance
GO:0040018	positive regulation of multicellular organism growth
GO:0046426	negative regulation of JAK-STAT cascade
GO:0048712	negative regulation of astrocyte differentiation
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060123	regulation of growth hormone secretion
GO:0060612	adipose tissue development
GO:0060613	fat pad development
GO:0090276	regulation of peptide hormone secretion