Version 5.4
Homo sapiens Protein: EPS8
Summary
InnateDB Protein IDBP-585789.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EPS8
Protein Name epidermal growth factor receptor pathway substrate 8
Synonyms DFNB102;
Species Homo sapiens
Ensembl Protein ENSP00000441888
InnateDB Gene IDBG-21563 (EPS8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 73 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 73 [view]
Protein-Protein 73 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016301 kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR011511 Variant SH3 domain
IPR013761 Sterile alpha motif/pointed domain
PFAM PF00018
PF14604
PF07653
PRINTS PR00452
PIRSF
SMART SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4DX66
UniProt Splice Variant
Entrez Gene 2059
UniGene Hs.609259
RefSeq
HUGO HGNC:3420
OMIM 600206
CCDS
HPRD 02563
IMGT
EMBL AC022073 AC073651 AC092753 AK301834 AK316134 AK316239 CH471094
GenPept BAG63278 BAH14505 BAH14610 EAW96355

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca