Version 5.4
Homo sapiens Protein: ZBP1
Summary
InnateDB Protein IDBP-586679.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZBP1
Protein Name Z-DNA binding protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000440552
InnateDB Gene IDBG-82385 (ZBP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003692 left-handed Z-DNA binding
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0032481 positive regulation of type I interferon production
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000607 Double-stranded RNA-specific adenosine deaminase (DRADA)
PFAM PF02295
PRINTS
PIRSF
SMART SM00550
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H171
PhosphoSite PhosphoSite-Q9H171
TrEMBL
UniProt Splice Variant
Entrez Gene 81030
UniGene Hs.302123
RefSeq NP_001153891
HUGO HGNC:16176
OMIM 606750
CCDS CCDS54478
HPRD 09484
IMGT
EMBL AJ300575 AK122761 AL035541 BC028218 CH471077 CT002036
GenPept AAH28218 BAG53713 CAC18810 CAI23107 CAM28299 EAW75511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca