Version 5.4
Homo sapiens Protein: COMMD4
Summary
InnateDB Protein IDBP-586743.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COMMD4
Protein Name COMM domain containing 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000433662
InnateDB Gene IDBG-23153 (COMMD4)
Protein Structure
UniProt Annotation
Function Down-regulates activation of NF-kappa-B. {ECO:0000269PubMed:15799966}.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:15799966}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR009886 HCaRG
PFAM PF07258
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H0A8
PhosphoSite PhosphoSite-Q9H0A8
TrEMBL
UniProt Splice Variant
Entrez Gene 54939
UniGene Hs.741298
RefSeq
HUGO HGNC:26027
OMIM
CCDS CCDS10277
HPRD 13083
IMGT
EMBL AK000459 AK314740 AL136872 AY542160 BC000837 BC068998 CH471136 CR533452
GenPept AAH00837 AAH68998 AAS22242 BAA91178 BAG37281 CAB66806 CAG38483 EAW99263

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca