Version 5.4
Homo sapiens Protein: PLBD2
Summary
InnateDB Protein IDBP-58775.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLBD2
Protein Name phospholipase B domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000280800
InnateDB Gene IDBG-58773 (PLBD2)
Protein Structure
UniProt Annotation
Function Putative phospholipase. {ECO:0000250}.
Subcellular Localization Lysosome lumen {ECO:0000269PubMed:17105447}.
Disease Associations
Tissue Specificity Ubiquitously expressed, with highest levels in heart, brain and liver. {ECO:0000269PubMed:17105447}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005764 lysosome
GO:0043202 lysosomal lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR007000 Phospholipase B-like
PFAM PF04916
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NHP8
PhosphoSite PhosphoSite-Q8NHP8
TrEMBL
UniProt Splice Variant
Entrez Gene 196463
UniGene Hs.115896
RefSeq NP_775813
HUGO HGNC:27283
OMIM
CCDS CCDS9168
HPRD 14116
IMGT
EMBL AC010178 BC030618
GenPept AAH30618

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca