InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IGLL5

Summary

InnateDB Protein

IDBP-588035.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IGLL5

Protein Name

immunoglobulin lambda-like polypeptide 5

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000431254

InnateDB Gene

IDBG-547140 (IGLL5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Contrary to IGLL1, not expressed in pre-B- cells. {ECO:0000269PubMed:1703205, ECO:0000269PubMed:1900243}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003823	antigen binding
GO:0005515	protein binding

Biological Process

GO:0006955	immune response
GO:0006956	complement activation
GO:0006958	complement activation, classical pathway
GO:0038095	Fc-epsilon receptor signaling pathway
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087	innate immune response
GO:0050776	regulation of immune response

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle